Publications

Our Papers

Since our lab was founded in September 2024:

1. Wang Z, Song K, Kim BS*, Manion J*. Sensory neuroimmune interactions at the barrier. Mucosal Immunol. 2024 Oct 5:S1933-0219(24)00104-1. doi: 10.1016/j.mucimm.2024.10.001. PMID: 39374664.

2. Kuziel GA, Lozano GL, Simian C, Li L, Manion J, Stephen-Victor E, Chatila T, Dong M, Weng JK, Rakoff-Nahoum S. Functional diversification of dietary plant small molecules by the gut microbiome. Cell. 2025 Feb 28:S0092-8674(25)00155-2. doi: 10.1016/j.cell.2025.01.045. PMID: 40056901.

Prior work:

1. Manion J#, Musser MA#, Kuziel GA, Liu M, Shepherd A, Wang S, Lee PG, Zhao L, Zhang J, Marreddy RKR, Goldsmith JD, Yuan K, Hurdle JG, Gerhard R, Jin R, Rakoff-Nahoum S, Rao M*, Dong M*. C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation. Nature 2023.

2. Manion J, Khuong TM, Harney D, Littleboy JB, Ruan T, Loo L, Costigan M, Larance M, Caron L*, Neely GG*. Human iPSC-derived GABAergic Interneuron Transplants Attenuate Neuropathic Pain. Pain February 2020; 161(2):379-387.

3. Manion J*, Waller M, Clark T, Massingham JN, Neely GG*. Developing Modern Pain Therapies. Frontiers in neuroscience. 2019 December 20; 13:1370.

4. Walters R, Manion J*, Neely GG*. Dissecting Motor Neuron Disease With Drosophila melanogaster. Frontiers in Neuroscience. 2019 Apr 12;13:331. doi: 10.3389/fnins.2019.00331. PMID: 31031583; PMCID: PMC6473072.

5.  Lau M, Manion J, Littleboy JB, Oyston L, Khuong T, Wang Q, Nguyen D, Hesselson D, Seymour J, Neely GG. Molecular dissection of box jellyfish venom cytotoxicity highlights an effective venom antidote. Nature Communications. 2019; 10(1):-.

6. Khuong T, Wang Q, Manion J, Oyston L, Lau M, Towler H, Lin Y, Neely GG. Nerve injury drives a heightened state of vigilance and neuropathic sensitization in Drosophila. Science Advances. 2019 July 10; 5(7):eaaw4099-.

7. Kokotović T, Langeslag M, Lenartowicz EM, Manion J, Fell CW, Alehabib E, Tafakhori A, Darvish H, Bellefroid EJ, Neely GG, Kress M, Penninger JM, Nagy V. PRDM12 Is Transcriptionally Active and Required for Nociceptor Function Throughout Life. Front Mol Neurosci.

8. Ford E, Pearlman J, Ruan T, Manion J, Waller M, Neely GG, Caron L. Human Pluripotent Stem Cells-Based Therapies for Neurodegenerative Diseases: Current Status and Challenges. Cells. 2020 Nov 20;9(11):2517. doi: 10.3390/cells9112517.

9. Khuong TM, Hamoudi Z, Manion J, Loo L, Muralidharan A, Neely GG. Peripheral straightjacket (α2δ Ca2+ channel subunit) expression is required for neuropathic sensitization in Drosophila. Philos Trans R Soc Lond B Biol Sci. 2019 Nov 11;374(1785):20190287.

10. Bondulich MK, Guo T, Meehan C, Manion J, Rodriguez Martin T, Mitchell JC, Hortobagyi T, Yankova N, Stygelbout V, Brion JP, Noble W, Hanger DP. Tauopathy induced by low level expression of a human brain-derived tau fragment in mice is rescued by phenylbutyrate. Brain. 2016 Aug;139(Pt 8):2290-306. doi: 10.1093/brain/aww137.

#Co-first, * Co-corresponding